Features
- Modular design for system expansion
- Easily
to link up with automated device (optional) for precision sampling from
Franz cells with automatic media replacement function
- User-friendly
program with HPLC online system available
- Designed
to test creams, lotions, ointments, and patches
The FDC-6 Transdermal
Diffusion Cell Drive Console is remarkably simple to use. Skin is mounted
between the cell cap (donor) and the cell body (receptor). The dermis is bathed
from below with an isotonic saline solution injected through a port provided
for that purpose.
Temperature is maintained at
37ºC by thermostatically controlled water that enters the lower port of the
water jacket and circulates out through an upper port. Warm water is supplied
and circulated by two (upper and lower) manifolds that are connected to a
constant temperature bath.
Homogeneous distribution of
temperature in the saline bathing solution is accomplished by the agitating
motion of a Teflon-covered magnetic stirring bar, driven by an external magnet
and mounted on a timing motor.
The cell cap is open to the
air, exposing the epidermis to the ambient conditions of the laboratory
environment. The open cap also allows for finite dose application of study
compounds to the epidermis by use of a micropipette or stirring rod.
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