- Heating block design for
parallel heating
- Interchangeable glass
cell volumes, no more broken Franz cells
- Manual or automatic
tilting system to purge air bubbles
- Modular
design for system expansion
- Designed to test creams,
lotions, ointments, and patches
- Built-in
sampling device
- New cleaner look with
light covers
- Patent
Pending
The DHC-6T Dry Heat Transdermal System is
remarkably simple to use, the DHBF Cells (Dry Heat Bubble Free Cells) are
constructed with molded Teflon donors and precision cut glass bodies. Skin is
mounted between the cell cap (donor) and the cell body (receptor). The dermis
is bathed from below with an isotonic saline solution injected through the
bottom port, which flows thru the upper port to provide contact with no bubbles
under the skin.
Temperature is maintained at 37ºC with a
thermostatically controlled heater block. Users can easily insert the DHBF
Cells into the cell slots, which will be maintained within ± .3°C of the set
temperature. Homogeneous distribution of temperature in the saline bathing
solution is accomplished by the agitating motion of a Teflon-covered magnetic
stirring bar, driven by an external magnet, which is mounted on a timing motor.
The cell cap is open to the air, exposing the epidermis
to the ambient conditions of the laboratory environment. The open cap also
allows for finite dose application of study compounds to the epidermis by use
of a micropipette or stirring rod.
All the DHBF Cells are installed in a light
protection chamber. The samples are taken from the bottom of each DHBF Cell
with pre-mounted syringes prior to the media replacement. All the DHBF Cells
tilt up while the media replacement is taking place to allow all the bubbles to
purge out.
Specification
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